Droplet Pack

Droplet generation pack

Turnkey system to easily generate droplets and control all key parameters.

All-in-one solution

Unbox. Set up. Get droplets.

Reproducible & easy generation

Produce highly monodisperse droplets (CV<3%)

Perfect for many applications

Particle generation, encapsulation, emulsions... and many more!

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Features & benefits

An all-in-one solution for droplet-based microfluidics

Do you want to implement droplet-based microfluidics? We designed a comprehensive solution based on our high precision instruments set. This Pack includes all you need to understand the droplet generation process from 0 to 1.

Get the Pack
Unbox the instruments
Install the setup following our step-by-step User Guide
Start generating your first droplets thanks to detailed protocols.

Start from scratch and quickly master all key parameters triggering and controlling droplet generation.

Droplet forming inside the microfluidic chip

Droplet forming inside the microfluidic chip

Benefit from the highest standards of microfluidic instruments

Microfluidics brings reproducibility and control over droplet size that are not achievable with any other technique.

Moreover, it is an ideal technique to handle ultra small volumes and control droplet generation precisely. It give you flexibility to easily generate identical droplets with the same content or to create individual droplets with unique payloads.

This Droplet Generation Pack includes our OB1 flow controller best-seller.

Thanks to the performance of this instrument, you will be able to generate:

Droplets ranging from 10 to 80µm diameter (and more using alternative microchips)
Highly monodisperse droplets (CV<3%)

Overview of the droplet pack setup

We can provide you with two Droplet Pack versions : the small version, to generate smaller droplets ranging from 10 to 40µm and the large version, for droplets ranging from 50 to 80µm diameter. Each Pack is composed of:

One OB1 flow controller with 2 control channels (one for each phase)
Two flow rate sensors (one for each channel)
Two fluidic resistances (for stable and accurate flow control)
Two Microchips from ChipShop, a leading microfluidic chip manufacturer.
All necessary reservoirs and tubings.

Schema Droplets generation setup

Application notes

- Emulsions generation & stability study
- Synthetic Organelles
- Nanoparticles & nanohydrogels
- Microgels
- Microbubble generation
- Liquid foam templating
- Single Cell Encapsulation
- Encapsulation
- Drug-delivery
- Microfluidic Droplets on demand
- Alginate beads production
- Droplets in microfluidics capillary
- Microfluidic flow focusing droplet generation

All our application notes

Reviews

- Introduction to droplet-based microfluidics
- Digital microfluidics using pressure driven flow
- Digital microfluidics: microfluidic droplets & emulsion science
- What is digital microfluidics?
- Researchers’ opinion on droplet generation in microfluidics: syringe pumps or pressure control?
- Droplet Sequencing (Drop-Seq)
- Droplets encapsulation for biological applications: a review
- Droplet detection and measurement in microfluidic channels
- Droplet production methods
- Sodium Alginate and applications: a review

All our reviews

Publications using our equipments

Image-based closed-loop feedback for highly mono-dispersed microdroplet production, Crawford et al, Scientific reports (2017)
High magnetic field gradient particle separation for biomedical applications. Conference Poster, Lennart Göpfert (2021).
Droplet microfluidics as a tool for production of bioactive calcium phosphate microparticles with controllable physicochemical properties, P. Habibovic et al., Acta Biomaterialia (2021).
3D flow-focusing microfluidic biofabrication: One-chip-fits-all hydrogel fiber architectures, Rui L. Reis et al. , Applied Materials Today (2021).
Thin film drainage dynamics of wheat and rye dough liquors and oat batter liquor, F. Janssen et al., Food Hydrocolloids (2021).
Coalescence Dynamics in Oil-In-Water Emulsions at Elevated Temperatures, B. Bera et al., Scientific Reports (2021)
Size-dependent particle migration and trapping in three-dimensional microbubble streaming flows Andreas Volk et al., Physical Review Fluids (2020).
High-Throughput Step Emulsification for the Production of Functional Materials Using a Glass Microfluidic Device Macromolecular Journals, D. Weitz et al.
Controllable generation and encapsulation of alginate fibers using droplet-based microfluidics Lab on a Chip, Nov 2015, A. J. deMello et al.
Image-based closed-loop feedback for highly mono-dispersed microdroplet production Scientific Reports, Sept 2017, G. Whyte et al.
Negative Pressure Induced Droplet Generation in a Microfluidic Flow-focusing Device Analytical Chemistry, Feb 2017, Say Hwa Tan et al

Droplet Pack Specification

Content of the pack

1 x 2-channel flow controller (OB1-2200)
2 x flow rate sensors
- Small version: 1 x MFS-D-2 (aqueous phase) & 1 x 2 x MFS-D-3 (oil phase)
- Large version: 2 x MFS-D-2 (aqueous / oil phase)
2 x flow resistances
- Small version: 1 x 22-H (aqueous phase) & 1 x 23-I (oil phase)
- Large version: 1 x 22-H (aqueous phase) & 1 x 22-I (oil phase)
2 x ChipShop microfluidic droplet chips
Reservoirs and holder
- 6 x reservoirs with their pressurized caps (2 x 50mL; 2 x 15 mL; 2 x 1.5 mL)
- 1 x quick connect reservoir holder (Wall-E holder)

And more!

Droplet Generation Pack User Guide

All necessary accessories: tubing, connectors, filters, etc…
1 x 10 mL vial of droplet oil (HFE-7500)
Control and automation software (Elveflow Smart Interface)
1 x User Guide which includes:
- Detailed contents list
- Step-by-step installation guide
- Detailed protocol to generate droplets with the Pack
- Screenshots and pictures to get familiar with our equipment.

Two versions available depending on the desired droplets

Our two versions only differ by the flow rate range of the oil phase.

The small version includes a MFS-D-3 allowing perfect feedback loop control of the flow rate to generate droplets ranging from 10 to 40 µm diameter.
The large version includes a MFS-D-2 allowing perfect feedback loop control of the flow rate to generate droplets ranging from 50 to 80 µm diameter.

Important note: our products are all intercompatible and you may acquire additional flow rate sensors or add extra products for specific applications. You will still benefit from the centralised ESI software control.

Droplet-based microfluidics

Droplet-based webinars

Droplet-based applications

Testimonials

“I found the systems quite robust, easy to connect and use”
Dr. Martino Chiara, ETH Zurich, Switzerland
OB1 pressure-driven flow controller user
“Thanks to Elveflow products, we can focus on our results rather than the tedious instrumentation. We especially appreciate the Elveflow system when it comes to droplet based systems which requires the control of multiple flows simultaneously. ”
Dr. Caglar Elbuken, Bilkent University, Turkey
OB1 pressure-driven flow controller user
“We are satisfied with the ELVEFLOW instrument, the regulation accuracy is well fitted with our applications. The advantage of this instrument is the capability it offers to easily move the experiments anywhere you want. This feature is very convenient, especially when we encapsulate cells into droplets in cell culture platforms.”
Pr. Annie Viallat, Adhesion & Inflammation Lab CNRS UMR 6212 Inserm UMR 600, France
OB1 pressure-driven flow controller user
“We are very satisfied of the ELVEFLOW pressure pumps! The ELVEFLOW pressure pumps enable us to perform portable experiments with accurate pressure control.”
Dr. Wiebcke Drenckhan, Liquids Interfaces Group of the Physic of Solids Lab - CNRS UMR 8502 Orsay University, France
OB1 pressure-driven flow controller user
“The advantages of this instrument are its ease of use and the accuracy of the regulated pressure. This feature is very convenient, especially when we perform foams and microfluidic.”
Dr. Pascal Panizza, Soft Matter Department of IPR – CNRS UR1 UMR6251, France
OB1 pressure-driven flow controller user
“I was suprised how quickly I was able to get things to work once I got going.”
Jamie Stover, Research Assistant, M. Zernicka-Goetz Lab at California Institute of Technology (Caltech)
OB1 pressure-driven flow controller user

Do you know how to implement droplet-based microfluidics?

Are you aware of how to compute shear stress and microfluidic resistance in your system?

Elveflow developped a microfluidic calculator that allows you to estimate all the key parameters at stake in your microfluidic system. Find out more below !

To help you determine your flow rate, pressure to apply, the best tubing resistance length for your setup, wall shear stress for biology applications, cell culture, and many more…

Elveflow provides its microfluidic calculator and…to make the most of our microfluidic calculator, find below a set of dedicated application notes:

More details about the droplet pack

A well-chosen microfluidic chip

The microfluidic chip is where the two immiscible phases (water and oil here) are precisely injected and mixed to generate monodisperse droplets (CV < 3%). The two microfluidic chips are made of Topas. Topas is a cyclic olefin copolymer (COC) resin which is a chemical relative of polyethylene and other polyolefin plastics.

Chip included in the droplet pack

A reservoir holder with 2 push-in connectors

Are you working with small samples or are you looking into manufacturing 100x mLs of emulsion? Elveflow offers a comprehensive range of reservoirs compatible with our OB1 Flow Controller, from 1.5 mL Eppendorf tubes to 100mL bottles.

droplet pack reservoir holder

Enhanced flow resistor systems

Flow resistances are used to increase the resistivity of the microfluidic system to improve the stability and control of the flow rate in the system.

Flow sensor and flow resistance

A complete user guide

Simple and intuitive instructions are provided to quickly and easily make droplets and control droplet generation parameters. When starting out, the user can follow step by step the provided protocol to obtain droplets of the specific size. In a second stage, the user can rely on the numerous tips provided and explore the “going further” section to complete its training in droplet generation and microfluidic flow control.

Need help or technical information?

Talk to an expert

For improved system management and prototyping, check out this modular ecosystem.

Find out more

Products and associated accessories

OB1 MK4

Microfluidic Flow Controller

1 to 4 channels pressure & vacuum microfluidic flow controller

Microfluidic flow sensor - MFS

Microfluidic flow sensor

Thermal flow rate sensor

Bronkhorst flow sensor - BFS

Premium Coriolis flow sensor

The Rolls-royce of flow sensors

RESERVOIRS

MICROFLUIDIC RESERVOIRS

Need help or advice?

For any help to determine what microfluidic instruments you need, you can contact us!
Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.