Microfluidic reviews
Our microfluidic reviews cover fundamental concepts and advanced topics, from air bubble management in microfluidic setups to PDMS compatibility in biological testing. With free access to in-depth guides, research summaries, and application notes, you can explore new possibilities in lab-on-a-chip systems, droplet microfluidics, and soft lithography fabrication.
What You’ll Learn from Our Microfluidic Reviews
Our collection of microfluidic reviews provides valuable insights into:
- Air bubbles in microfluidic setups – Methods to prevent and remove bubbles that can disrupt fluid flow.
- Microfluidic droplet sequencing – Understanding how microfluidic platforms are transforming genomic studies.
- PDMS compatibility for biological testing – Analyzing how polydimethylsiloxane interacts with biological samples.
- 3D cell culture methods – Exploring microfluidic approaches to tissue engineering and regenerative medicine.
- Getting started with soft lithography – A guide to fabricating microfluidic devices with high precision.
Additional Open-Access Resources
Beyond our microfluidic reviews, we offer free-access content to help you stay informed and optimize your research:
- Research Summaries – Stay updated with the latest discoveries and innovations in microfluidics.
- Application Notes – Step-by-step guides to setting up and optimizing microfluidic experiments.
- Microfluidic Videos and Images – Scientific visuals, device demonstrations, and artistic representations of microfluidic phenomena.
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Microfluidics for Enhanced Oil Recovery studies
Explore how microfluidics is advancing Enhanced Oil Recovery (EOR) research, from fluid rheology to foam-based injection and nanoparticle suspensions.
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Microfluidics in Cosmetic Research: Improved Formulations and Smarter Testing
Explore how microfluidics is revolutionizing cosmetic research from formulation to toxicology with ethical, precise, and scalable testing.
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Microfluidics for the diagnosis and treatment of tuberculosis
Microfluidics for the diagnosis and treatment of tuberculosis
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Acoustofluidics: Cutting-Edge Techniques for Microfluidic Particle Manipulation
Revolutionizing Microfluidics with Acoustic Particle Manipulation
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Flow control in microfluidics device
There are three main classes of systems to control liquid motion in microfluidic and nanofluidic devices.
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Microfluidic low-flow liquid flow meters: a review
Microfluidic low-flow Liquid flow meters are a compulsory element of microfluidic systems requiring a control of the sample volume dispensed and/or, obviously, the sample flow rate.
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Microfluidic T-junction
This short note will introduce you to the key takeways about microfluidic T junction among other microfluidic junctions.
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Fluid mixing
Fluid mixing at microscale is of importance for many fields of application. This short review summarises the key takeaway aspects of fluid mixing at microscale.
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Syringe pumps and microfluidics
In the past two years, several new microfluidic syringe pump systems have changed the use of syringe pumps in microfluidic experiments.
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Magnetic particle separation : a short review
This review presents a few examples of applications where magnetic flux sources, magnetic particles and microfluidics are combined in order to perform particle sorting and handling.
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Microfluidic mixers : a short review
In microfluidic laminar flows, traditional turbulent mixing between two liquids cannot occur. However, controllable and fast mixing is critical for microfluidic and lab-on-chip devices. So different mixing techniques were developed and are here presented.
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Researchers’ opinion on flow control for microfluidics
One of the great challenges for researchers using microfluidics is miniaturizing analysis processes in very small microchip.
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Responsiveness of flow control instruments
Microfluidic flow controllers are designed to control flows in microfluidic chips.
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Tricks and Tips to Enhance your Microfluidic Flow Control
Despite their sturdiness & simplicity, syringe pumps are often problematic in microfluidics.
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Microfluidic flow control
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Liposome and Lipid Nanoparticle – An overview
This review gathers a collection of information regarding liposome and lipid nanoparticle from their use and applications to how to generate them by bulk
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Introduction to Droplet-Based Microfluidics
Droplets formed within microfluidic channels often serve as microreactors containing different chemical or biological compounds, allowing massive numbers of independent reactions to be performed rapidly using a minimal amount of total reagent.
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Confined particles in microfluidic devices: a review
Brief overview of the numerous advantages of confined particles like bubbles, droplets and fibers and how confinement can be used for various applications
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Droplet production methods
The review summarizes the various droplet production methods available from microfluidics to the more commun batch method.
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Sodium alginate and applications: a review
This review focuses on sodium alginate and its applications in microfluidics
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Digital microfluidics using pressure driven flow
Making droplets in a capillary or a microfluidic device is often met with two problems
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Digital microfluidics: microfluidic droplet and emulsion science
Microfluidic technologies offer an efficient means of producing highly uniform droplets and bubbles, and also a convenient mechanism for manipulating their downstream motion.
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What is digital microfluidics?
Digital microfluidics is an alternative technology for microfluidic systems based on the design, composition and manipulation of discrete droplets and/or bubbles.
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Droplet-Sequencing (Drop-Seq)
Drop-Seq is a strategy based on the use of microfluidics for quickly profiling thousands of individual cells simultaneously by encapsulating them in tiny droplets for parallel analysis. This review presents the techniques and applications of Drop-Seq.
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Researchers’ Insights on Droplet Generation in Microfluidics: Syringe Pumps vs. Pressure Control
Droplet generation in microfluidic, the aim of this technology is to create fluid-fluid dispersion into channels
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Generate droplets in a microfluidic capillary
It is possible to make droplets in a microfluidic capillary with commercial tools, especially chromatography tools. One can easily make droplets...
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Droplets and digital microfluidics
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Water-in-Oil Emulsions: Mechanisms, Applications, and Innovations
Learn about water-in-oil emulsions and how Elveflow’s microfluidic solutions offer precision control for applications in food, cosmetics, and pharmaceuticals.
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Laminar flow and capillary flow in microfluidic chips
The profile of laminar flow through a small straight pipe may be approximated by small concentric cylinders towards the direction of the flow.
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Microreactors & Microfluidics in Chemistry – a Review
This review introduces the field of microfluidics and provides an overview of the advantages, disadvantages, and current applications of microfluidics in chemistry.
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Air-Liquid Interface and Optimized Cell Culture Substrates for Microfluidic Lung-on-a-Chip Applications
Explore the intricacies of air-liquid interfaces and optimized cell culture substrates in microfluidic lung-on-a-chip systems.
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Microfluidic Tumor-on-Chip Systems for Breast Cancer Research
Explore the advanced microfluidic tumor-on-chip systems revolutionizing breast cancer research. How these systems offer precise drug testing.
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Droplet Detection and Measurement in Microfluidic Channels: An In-Depth Analysis
Explore methods for droplet detection and measurement in microfluidic channels, including optical imaging and laser-initiated detection.
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Gut-on-Chip: Advancing Intestinal Research
Discover how gut-on-a-chip technology is revolutionizing intestinal research & drug development by replicating the gut's complex environment.
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Emerging Trends in Microfluidics
Centrifugal microfluidics, or "Lab-on-a-CD," leverages centrifugal force to manipulate fluids on a microscale.
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Advancements in Centrifugal Microfluidics
Centrifugal microfluidics, or "Lab-on-a-CD," leverages centrifugal force to manipulate fluids on a microscale.
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NANOCRYSTALS IN MICROFLUIDICS
Nanocrystals (NCs) are tiny crystalline objects, with unique properties crucial for scientific and technological applications.
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CRISPR-CAS9 and its Relation with Microfluidics
The integration of CRISPR-Cas9 with microfluidics has led to the development of innovative techniques for genetic editing and screening.
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Microfluidics Devices in Pharmacogenomics Paving the way for precision medicine
Pharmacogenomics is the study of how an individual’s genetic variants influence drug responses and treatment efficacy.
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The Dynamics of Fungal Spore Dispersal: Insights from Microfluidic Models
The Dynamics of Fungal Spore Dispersal: Insights from Microfluidic Models
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Exploring Free Flow Electrophoresis: A Comprehensive Review
Free-flow electrophoresis (FFE) is a technique that enables the continuous separation of analytes as they flow through a planar channel.
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General microfluidics
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Microfluidic cell culture – a beginner friendly review
Microfluidic cell culture is an innovative technology to improve classical lab protocols
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Microfluidic flow cells: off-chip pH monitoring for organ-on-chip
Microfluidic flow cells with embedded optical sensors, have been the most common choice for microenvironment monitoring like pH control.
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Microfluidics for sperm sorting: a review
Microfluidic systems have an important role to play in the democratization of sperm sorting technologies as well as improving existing techniques...
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Microfluidic for cell biology: Concepts and methodologies
Cell Biology: Microfluidic Concept and methologies for biologists to control the complete cellular microenvironment with microfluidics.
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Perfusion for live-cell imaging: A review
Live-cell imaging is a non destructive method which focuses on the observation of live cells and is widely used in cellular biology research and biomedical industry. This short review will present some technical aspects and challenges encountered in this field. Nowadays, the most widely used cell culture system is the static culture, where the cells are cultivated inside Petri dishes or multiwall plates. In static culture, the culture medium is supplied in a batch-wised manner.
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Label-free microfluidic cell separation and sorting techniques: a review
In this review we will describe some label-free microfluidic techniques to accomplish cell separation and sorting.
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Microfluidic chambers for cell culture: Medium change
Ability to switch drugs in seconds or less in microfluidic chambers allows studying cell response at cells timescale.
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PDMS in biology research: A critical review on PDMS lithography for biological studies
PDMS advantages and drawbacks for cell biology are here discussed.
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Perfusion for live cell imaging: Methods and techniques
This short note summarizes the methods and techniques employed to perform perfusion for live cell imaging and critical issues encountered.
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Imaging and microscopy: Perfusion chambers
The first live-cell imaging chambers were designed in the early twentieth century, shortly after mammalian cell culture techniques were developped
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Perfusion for live cell imaging: Methods and Systems
Live-cell imaging is a non destructive method which focuses on the observation of live cells and is widely used in cellular biology research and biomedical industry. This short review will present some technical aspects and challenges encounter in this field.
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A Review of heating and temperature control in microfluidic systems: Techniques and Applications
This review presents an overview of the different techniques developed over the last decade to regulate the temperature within microfluidic systems.
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Cell deformation using microfluidic chip
Cells growth, gene expression and differentiation are often related to mechanical environment such as confinement or applied stresses.
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Gradients generation for cell biology in microfluidics
Chemical gradients play a key role in many biological processes and regulate a number of cellular functions in vivo. Indeed, there are several examples of gradient-dependent phenomena in nature.
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Microfluidics for cell biology
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Organoids VS Organ-on-a-chip: A Comparative Review of Advanced In Vitro Models
Discover the transformative potential of organoids and organ-on-a-chip technologies in advancing drug testing, disease modeling, and personalized medicine
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Liver-on-chip: keeping up with the technology
The liver is involved in more than 300 vital functions, but is mainly known for being part of the digestive tract, where it has the extremely important role of metabolizing both xenobiotics and nutrients (carbohydrates and lipids).
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Lab-On-a-Chip drug testing in Microfluidics
Lab-On-a-Chip drug testing in Microfluidics
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Exploring Organ-on-a-Chip Technology: A comprehensive review
Exploring Organ-on-a-Chip Technology: A comprehensive review
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3D Cell Culture Methods and Applications
Cell culture consists in growing cells in an artificial environment in order to study their behavior in response to their environment[1]. Different kinds of cell cultures can be found nowadays, and some would be more suited than others depending on its properties and applications.
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Organs on chip review
Multi-organs on chip could also allow us to witness the side effects of certain drugs on different organs, not limited to those that the treatment targets.
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Microfluidic “mini-brains”: keeping up with the brain-on-chip technology
At the beginning of the third millennium, due to prolonged aging, neurodevelopmental disorders are growing and a much deeper understanding of the brain is necessary.
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Coronavirus (SARS-CoV2) diagnostic with microfluidics
Coronavirus (SARS-CoV2) diagnostic through microfluidics
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3D cell culture: market and industrial needs
In this report, we identify the following two main purposes for the 3D cell market
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Heart-on-chip
A heart-on-chip is a microfluidic chip reproducing the mechanisms of a heart, in order to test medicine quickly and observe the reaction of heart cells. Great care is given to mimic the mechanics of a heart in an artificial structure, lined with live heart cells.
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Lung-on-a-Chip: History, Origins and Development
While many animal models have been used to study lung diseases, they lack sufficient similarity with human systems, leaving gaps in what is possible in animal-based platforms.
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Recent research breakthroughs in lung-on-chip technology
It could be extremely interesting to build a human-on-chip that will model the interactions between different organs, but it is also essential to develop simulations of tissue-tissue interfaces and more generally of local organ behavior.
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Organ-on-a-chip
Since 2012, more and more people, companies or lab, have worked on the organ-on-a-chip. These cell cultures can, thanks to microfluidics, mimic the cells microenvironment of the human body. Thus, these chips could become wonderful search accelerators and we can hope that, in ten years, they could replace the animal testing. Finally, organs on chips could lead us to personalized medicine.
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Organ-on-chip companies
Organ-on-chip companies developping innovative technologies
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Organs-on-chip & 3d cell culture
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Circular channel fabrication in microfluidic devices
Microfabrication techniques for a circular channel
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Soft lithography SU-8 Coating
In soft lithography, the fabrication of a mold, often made in SU-8, is required for replicating PDMS microfluidic structures.
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Soft Lithography: SU-8 baking
Replicating PDMS-based structures first requires the fabrication of a SU-8 master mold that will serve as a patterned template for PDMS casting
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SU-8 photolithography: UV exposure
How do you perform a successful SU-8 exposure? Here you will find the tips and tricks to do it.
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SU-8 photolithography: Baking
How do you perform a successful photoresist baking? Here you will find the tips and tricks to do it.
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SU-8 photolithography: Spin-coating
How do you perform a successful spin coating? Here you will find the tips and tricks to do it.
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PDMS membrane: thickness of a spin coated PDMS layer
The final PDMS layer thickness mainly depends of spin-coating speed and duration.
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SU-8 mold lithography
Here you can find a complete overview of a SU-8 mold fabrication process.
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PDMS softlithography
Here you can find a complete overview of a PDMS chip replication.
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Introduction about soft-lithography for microfluidics
Unlike photolithography, soft lithography can process a wide range of elastomeric materials, i.e. mechanically soft materials.
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Microfluidic fabrication
There are different techniques to make microfluidic devices. The main ones are etching, thermoforming, polymer ablation and polymer casting
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Fabrication of Glass and Film Photomasks
The photolithography mask is an important tool in soft photolithography processes, we explain here how they are made
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SU-8 photolithography : UV sources
A UV Lamp to expose your SU-8 photoresist. You will find here the relevant points to think about.
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PDMS Soft lithography : Plasma cleaner
A plasma cleaner to bond your PDMS chip, you will find here the relevant points to think about.
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Soft Lithography & microfabrication
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