Check our recircualtion loop use case for unidirectional microfluidic experiments
The fluid remains in the incubator, reducing the possibility of bubbles forming with the MFS+
Easier to use
No USB or electrical connection is required
In microfluidics, generating a gradient of concentration involves creating a gradual variation in the concentration of a substance across a microchannel.
Different method can be used to generate a gradient in microfluidics:
This method relies on the natural process of diffusion where two or more fluids containing different concentrations of a substance flow adjacent to each other in a microchannel. Over time, diffusion occurs between the streams, creating a smooth gradient of concentration. The design of the channel and the flow rates of the fluids control the steepness and shape of the gradient.
A microfluidic gradient generator can be designed using a tree-like network of branching channels. In this approach, two or more fluids with different concentrations are split and recombined in a series of junctions, effectively diluting the substances step by step. This allows for a highly controlled gradient over the length of the channel.
Surface: concentration (mol/m³)
Depending on the initial concentration, flow rate and namely of the geometry for each section the gradient obtained can be totally different. The serpentine design in each section allows the diffusion to occur and to get a uniform concentration before the next section.
Here an example of a set-up to create concentration gradients using a “Tree-like” device. The flow is generated using an OB1 pressure controller and monitored by two flow sensors that provide two solutions in the gradient generation chip. The third inlet is closed because it is not used in this example.
The set-up contains:
Gradient concentration can be used in many applications here is a non exhaustive list:
Don’t hesitate to set up a meeting with one of our microfluidics experts. We’re here to help you explore the wide range of possibilities for your experiment. Our team can guide you through every step, offering insights and support tailored to your research goals. Let’s collaborate to make your experiments a success!
Indeed! Our professionals will determine which tools are most appropriate for your application, including the kind of flow sensor and the quantity of flow controller channels required for your experiment. Use the yellow “talk to our experts” button above to get in touch with us.
You can order our instruments on the product section of our website.
Do-it-yourself fluid concentration gradient using microfluidics
Use the laminarity of microfluidics flow to get quickly a controlled gradient
From linear to logarithmic gradient, more or less smooth, create the specific gradient you need
Can be used for many applications such as cell culture, toxicology, chemical reaction, crystallization
For any help to determine what microfluidic instruments you need, you can contact us! Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.
Get a quote
Name*
Email*
Message
Newsletter subscription
We will answer within 24 hours
By filling in your info you accept that we use your data.
Collaborations
Need customer support?
Serial Number of your product
Support Type AdviceHardware SupportSoftware Support
Subject*
I hereby agree that Elveflow uses my personal data Newsletter subscription
How can we help you?
Message I hereby agree that Elveflow uses my personal data Newsletter subscription