Best Practices for Single-Cell Analysis Across Modalities 22 August 2024 By louise Best Practices for Single-Cell Analysis Across Modalities Introduction Single-cell technologies have revolutionized our understanding of cellular heterogeneity, enabling the simultaneous profiling of multiple molecular modalities. This review outlines best practices for the comprehensive analysis of single-cell data across different modalities, providing guidance on integrating and interpreting these diverse datasets. Cellular state is characterized by various … Continued
Microfluidics-free single-cell genomics with templated emulsification 15 August 2024 By louise Microfluidics-free single-cell genomics with templated emulsification Introduction Single-cell RNA sequencing (scRNA-seq) has fundamentally transformed the understanding of cellular heterogeneity by enabling the transcriptional profiling of individual cells. Traditional scRNA-seq methods heavily rely on microfluidic devices, which, despite their precision, have limitations such as high costs, complex operation, and restricted throughput. These constraints hinder widespread adoption, … Continued