Key Applications of Pressure-Based Flow Controllers

Thanks to their superior control, pressure controllers like the Elveflow OB1 have found applications in a wide range of microfluidic experiments, including:

1. Droplet Microfluidics

Precise control of fluid flow is crucial for droplet generation, where monodispersed droplets are created for applications in drug screening, emulsions, and encapsulation of biological materials. Pressure-driven flow ensures uniform droplet size and high reproducibility, making it ideal for high-throughput analysis.

2. Polymer Synthesis

In microfluidic polymerization processes, maintaining consistent flow rates is essential for producing uniform polymer structures. Pressure-based flow controllers provide the stability required for precise control of reaction conditions and polymer formation.

3. Cell Culture: Cell Perfusion

For cell perfusion experiments, pressure controllers offer a gentle and consistent flow that mimics physiological conditions, enabling the study of cell behavior in microfluidic environments with minimal shear stress. This is critical for tissue engineering and regenerative medicine applications.

4. Cell Confinement Assays

Microfluidic systems often require precise flow regulation to confine cells within specific regions for long-term monitoring. Pressure controllers allow fine-tuned fluid manipulation to facilitate cell trapping and real-time imaging.

5. Organ-on-a-Chip Systems

Organ-on-a-chip platforms rely on controlled fluid dynamics to mimic the complex microenvironments of human organs. Pressure controllers provide the flow precision needed for recirculating media and delivering nutrients without pulsation, enhancing the physiological relevance of such models.

6. Recirculation Studies

In experiments that require continuous fluid recirculation, such as drug testing and dynamic cell culture, pressure-based flow control ensures stable and contamination-free operation over extended periods.

Elveflow Systems Adapted to Various Applications

To cater to the diverse needs of microfluidic researchers, Elveflow offers specialized microfluidic systems that provide comprehensive solutions for various applications. Our experts will customize your setup according to your needs for the following applications: 

Droplet Generation:

Optimized for microdroplet production, emulsions, and encapsulation studies. This system includes pressure controllers, flow sensors, and accessories tailored for precision droplet formation, ensuring high reproducibility and efficiency.

Cell Perfusion:

A complete solution for cell culture studies, providing smooth and controlled media perfusion to support long-term cell growth and analysis under physiological conditions.

Organ-on-a-Chip:

Elveflow systems provide the necessary pressure control and fluid handling capabilities to replicate in vivo conditions for organ-on-a-chip experiments, enabling researchers to simulate complex biological environments with precision.

Recirculation :

Ideal for experiments requiring long-term recirculation of fluids with minimal evaporation and contamination, such as drug screening and environmental studies.

Sequential Injection:

Designed for experiments that require the precise delivery of multiple fluids in sequence, such as reagent mixing, biochemical assays, and reaction kinetics studies. With automated flow sequencing, researchers can achieve high accuracy and reproducibility without manual intervention.

Each of these tailored solutions simplifies experimental setup and enhances reproducibility, allowing researchers to focus on their scientific goals without the complexities of flow control issues.

Conclusion

Pressure-based flow controllers, such as the Elveflow OB1, represent a significant advancement in microfluidics, offering unparalleled precision, stability, and flexibility over traditional syringe and peristaltic pumps. Whether for droplet microfluidics, cell culture, or organ-on-a-chip applications, these controllers provide the necessary control to achieve consistent and reproducible results.

By offering tailored microfluidic systems, Elveflow has made it easier than ever to integrate precise flow control into a variety of research applications, empowering scientists and engineers to push the boundaries of microfluidic innovation.

Visit our website and schedule a call with our experts to learn how we can help upgrade your experimental setup with precision flow control solutions.