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Biomarkers for the prediction and prevention of brain disorders

First stage deadline : 19th September 2023

Elvesys – the ideal SME partner for your Horizon Europe consortium!

Elvesys is a French SME whose expertise includes microfluidic instrumentation and flow control systems for organ/tissue-on-chip systems and automated cell culture. We would be excited to support you in developing your in vitro model for fluid biomarker validation and to contribute our expertise in the elaboration and management of Horizon Europe projects under the call “Validation of biomarkers for the prediction and prevention of brain diseases”. Contact us to discuss your project idea!

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Why should you use microfluidics for your biomarker-related experiments?

  • Organ-on-chip platforms can replicate human organs or tissues remarkably well
  • Perfusing your organ-on-chip device enables injection of media and drugs in programmed sequences
  • We develop automated tools that simplify researchers’ and pharmaceutical companies’ access to microfluidics technology
  • Microfluidics paves the way for less animal testing and more reproducible results for biomedical research
Elveflow and Elvesys key figures for industrial partnership projects

Elvesys can be your perfect industrial partner for the call HORIZON-HLTH-2024-DISEASE-03-13-two-stage

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Elveflow and Elvesys key figures for industrial partnership researchers

Validation of fluid-derived biomarkers for the prediction and prevention of brain disorders

What can microfluidics do for the validation of biomarkers related to brain disorders?

Through microfluidic perfusion of the medium of your cell culture, you can obtain control of microphysiological conditions that closely resemble the real environment of cells in the human body. Controlled perfusion can add shear stress to the cell culture, which is necessary for cell maturation and differentiation. Pharmaceutically active compounds can be added to the in vitro cell culture with high precision, and samples can be taken continuously rather than just at specific time points. If necessary, you can observe the cells under the microscope and take images at any time. This way, the objectives of the call Validation of fluid-derived biomarkers for the prediction and prevention of brain disorders can be met in an innovative manner.

  • Development of new in vitro biomarker validation models for biomedical research

⇒ There is an urgent need to improve diagnosis, drug discovery, and the development pipeline to increase the success rate of new therapeutics (for cancer drugs it is only 3.4%) and enable earlier detection and treatment. Microfluidic cell-based assays and analyses are among the most promising strategies, supported by direct feedback from industry and regulatory authorities.

  • Organ- and tissue-on-chip systems in disease modeling

⇒ Animal testing is increasingly restricted by European regulations. Cell cultures on microfluidic chips allow the microenvironment of the cells to be reproduced very accurately, both in terms of the chemicals that come into contact with the cells and the physical parameters (temperature, shear stress on the cells, etc.). They are therefore much more meaningful human models than conventional cell cultures and are excellent candidates for replacing animal experiments in biomedical research.

Let’s start new projects together!

World’s biggest industrial microfluidic lab. Strong experience in European projects.
The ideal SME partner!

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What we can do for the “Validation of fluid-derived biomarkers for the prediction and prevention of brain disorders” call, as an SME partner:

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For this Horizon Europe call on biomarker validation, we can bring our expertise in microfluidic instrumentation and flow management to help you develop a dynamic cell culture or an organ-on-chip platform for your project that can be automatised and user-friendly.

Specifically, Elvesys can:

  • Support the development of novel in vitro models
  • Propose a user-friendly organ-on-chip system to recreate the human microphysiological environment
  • Automatize the fluid handling inside your system, including media perfusion and drug administration

Elvesys as a microfluidic SME partner

Our SME already brings its expertise in microfluidics to several Horizon Europe projects:

Logo Lifesaver Elvesys
Alternative Logo ELV microfluidics in vitro system biomedical research
01 LOC AI logo 300DPI

LIFESAVER

Pharmacological risk assessment using a bio-digital twin

ALTERNATIVE

Environmental toxicology assessment via a microfluidic cardiac tissue model

LOCAI

Artificial Intelligence for microfluidic cell culture monitoring

Looking for information about Research and Innovation Actions (RIA)? You can have a look at our RIA page.

Need a partner for your HORIZON-HLTH-2024-DISEASE-03-13-two-stage consortium?

Contact us

We would be glad to join your project to help you to develop a microfluidic system for your specific applications, and share our experience with project submission, innovative product development, and dissemination.

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