contact@elveflow.com+33(0).184.163.807+1(414)-406-4343 Elveflow is an Elvesys brand, an international microfluidics innovation center with high level researchers dedicated to microfluidics and organ-on-a-chip.
Droplet based microfluidics
Custom manufacturing of microfluidic plastic cartridges
AchiraLabs experienced chip designing team can help you through the design, prototyping and fabrication of lots of small microfluidic chips in PDMS, thermoplastic materials or make a silicon master with SU-8 for your specific application.
Accelerated microfluidic development; with this microfluidic company, go from design to device in less than two weeks. ALine has a set of engineered fluidic components such as valves, pumps, vents, and metering channels, that can be readily integrated into a custom chip to support a variety fluidic workflows and with semi-automated control using the ADEPT pneumatic controller.
Polymer & glass microfluidic chips
Also probably one of the most famous microfluidic companies for polymer chips. ChipShop also provides glass microfluidic devices with and without electrodes. They have a wide catalog of standard microfluidic chips for various microfluidic applications. They also provide full custom microfluidic chips either in small quantity & mass production.
Glass chips and metallization technology
CMC Microsystems provides microsystem research with industry-calibre resources, access to state-of-the-art prototyping technologies, tools for test and support services.
CMC is a microfluidic company providing design environments CAD tools for design and fluidic analysis with finite element analysis technique, prototype manufacturing services, technology files and user guides for manufacturing process, engineering support.
Standard glass microfluidic chips
Dolomite microfluidics provides standard glass microfluidic devices for the main microfluidic applications, especially droplets.
PMMA & PEEK microfluidic devices
Epigem has the particularity to provide both PMMA & PEEK microfluidic devices. This microfluidic company provides full custom microfluidic devices either for small volume or mass production.
This applies considerably when the mask is made of polyester film, and to a lesser degree when it is glass-made. Those dimensional changes of the photolithographic mask will lead to dimensional changes of your microfluidic channel. For some microfluidic applications, small changes in the microfluidic channel size can lead to strong changes of your fluidic resistance.
The dimensions of a film photolithographic mask will change under the influence of 4 factors: changes in temperature, changes in humidity, mechanical tensions and aging. Some dimensional changes are reversible, whereas others are not.
The dimensions of a glass photo-mask will only change with two of these factors; temperature and mechanical tensions, so movement due to humidity is avoided.
Because humidity is probably the hardest of these 4 factors to control adequately – and also has the biggest influence on dimensional changes – glass photolithographic masks would always be the recommended product if you need to control the accuracy of the mask to critical dimensions.
Film is made up of a polyester base with a thin layer of gelatin on its surface. Both the polyester and the gelatin absorb moisture from the air. The more water they absorb the more they swell (size increases). Respectively, they shrink as they dry out. The moisture content of the film will gradually adjust to the moisture content of the air (known as Relative Humidity RH). RH represents the amount of water that air can hold as a percentage at that particular temperature before condensation appears.
Glass and film will also dimensionally change with temperature – however, this is probably the easiest of the 4 factors to control, and one that in relative terms differs very little from one part of a production environment to another. Even in a normal office environment, it’s rare that conditions drop below 15deg or raise above 27deg, so a 6 degree swing is the most that we would expect in normal conditions. However, humidity can swing massively by up to 30-40% without even being noticed.
Hence, glass is ‘king’ when it comes to dimensional changes. (There are also differences in stability between the different glasses. Soda Lime, whilst being more than 10 times better than polyester film, still has a long way to go to beat the tight low CT of Quartz.)
Thermoplastic & PDMS microfluidic devices
FlowJEM is a microfluidic company from Toronto, which provides full custom PDMS microfluidic device, and Polycarbonate, Cyclicolefin polymer and Acrylic thermoplastics microfluidic devices.
Customized Microfluidics Devices
Based on the MEMS foundry service, personal expert advice and all peripherals around the chip, iX Factory offers fabrication and project work. These services are basically very diverse. Based on your needs and goals, iX Factory adapts the services. iX Factory offers various solutions from development to prototyping to batch production. iX Factory specialises in microreactors, lab-on-a-chip, integrated optics, MEMS structures, as well as, in (Bio)MEMS.
Glass microfluidic devices
Klearia is a French innovative microfluidic company which provide glass microfluidic devices with and without electrodes. Since Klearia are still a small company they are quite open to offering some exotic development and attractive price.
Customized glass (fused silica and borosilicate) chips
LioniX is a leading provider in development and small to high volume production of leveraging and innovative products based on microsystem technology and MEMS. Their core technologies are integrated optics and microfluidics. LioniX also provides MEMS foundry services.
Glass, quartz & silicon microfluidic chips
Micralyne has the particularity to be able to also provide sensors, MEMS and optical MEMS. If you need complex full custom microfluidic devices integrating sensors or any micro-machined active elements.
Flexible polymer microfluidic chips
Microflexis provides thin and flexible polymer microfluidic devices. They provide thin polycarbonate (PC) and polystyrene (PS) microfluidic chips. They also provide full custom microstructured polymer film and polycarbonate (PC), polymethylmethacrylate (PMMA), polystyrene (PS), polypropylene (PP), polyethylene terephtalate (PET) and cyclic olefin polymers (COP, COC) microfluidic chips.
Polymer, glass & silicon microfluidic chip
MicroLabDevice provides microfluidic chips based on polymers and offers a range of fabrication methods depending on design, volume and whatever features are required to be integrated. They have techniques for integrating valves, powders, reagents and electrodes, to make the diagnostic cartridges smarter, self-contained and low-cost. They offer a custom fabrication service where they can build chips to your design and you might benefit from some of their standard designs in their catalogue or if you want a fully-fledged system with a custom cartridge they can also help with that too.
Help the industrialization of microfluidic devices
microLIQUID is a company that designs, prototypes and manufactures disposable microfluidic cartridges for the IVD, VET and Point of Care industries. microLIQUID has also developed a range of devices to adapt Elisa-style tests perform in the lab to point of care analysis, opening a window for commercialization of the test in environments where immediate availability and fast results is necessary. microLIQUID does not enter the IVD, VET or POC markets, microLIQUID is offering a new tool to those companies in this markets that can be used with a range of samples (serum, salive, urine) to obtain quantitative or qualitative assays in non laboratory locations.
MicroMed Solutions, a division of LasX Industries, is a full-service CDMO—deploying microfluidic technology and thin-film laser converting to bring point-of-care devices to the marketplace. They specialize in transitioning prototypes to manufacturable point-of-care devices—guiding clients every step-of-the-way with their deep understanding of the medical device regulatory environment.
Plastic cartridge by injection molding
Micronics provides custom design and development services – including prototype to commercial development of stand-alone disposable cartidge/instrument systems.
Polymer, glass & silicon microfluidic chips
Probably one of the most famous microfluidic glass chips foundry, Micronit also provides since 2014 microfluidic chips using various polymers and also silicon microchips. They can integrate various types of electrodes in their chips and have an interesting range of chip holder. They provide either standard chips or full custom development of microfluidic devices and can provide microfluidic chips both in small or mass production industrial quantity.
Polymer Microfluidic Chips
Glass Microfluidic Chips
MicruX develops reusable microfluidic electrophoresis chips manufactured on highly resistant hybrid SU-8/Pyrex material. Moreover, chips are fabricated with integrated electrodes on the pyrex cover plate. The innovative microfluidic chips provide a long life (over 1000 runs/injections) with a low-cost, high efficiency and precision.
Various polymer microfluidic devices
MiniFAB takes care of every steps from the conception of the microfluidic device to its packaging for commercialization. MiniFAB provide PMMA, ABS, PVC, PET, COC, COP, PI, PEEK, PP, PU, PS and others polymer full custom microfluidic devices. MiniFAB can integrate various thin film materials such as Al, Cu, Au, Cr, Ti, Ni, W or parylene.
Injection molded polymer microfluidic chips
NILT offers production of polymer microfluidic chips by injection molding – both small series and high volume manufacturing are offered. This microfluidic company can make chips with multiple channel depths and with sub-100 nm to several 100 µm channel widths.
Polymer PMMA & PS microfluidic chip
SIMTech provides a range of polymer microfluidic chips such as PS or PMMA and chipholder. This microfluidic company can provide either standard chips for common microfluidic applications or full custom chips for a given applications.
Polymer Microfluidics Devices
Sony DADC BioSciences is a leading OEM supplier of smart polymer-based consumables to the in-vitro diagnostics, life sciences and medical technology industries as well as selected segments of the electronic industry. Sony DADC offers full solutions for the fabrication of macro-, micro-, nano-structured and multi-layer polymer devices.
PDMS Microfluidics chips
The Stanford microfluidics laboratory was one of the only foundries which proposed custom made multilayer PDMS microfluidic chips which integrate quake valve. Stanford Microfluidics Foundry has now stopped this activity.
Polymer microfluidic device
ThinXXS provides polymer microfluidic chip development and manufacturing mainly for biomedical application. ThinXXS seems to be a microfluidic company mainly adapted to customers who want to develop their biochip for commercial application.
Glass microfluidic devices & microfluidic glass mold for PDMS casting
Trianja provides micro and nanofluidic glass chips with resolution down too 100nm. This microfluidic company also provides glass mold for PDMS casting and hot embossing.
Micro and nano-scale patterned substrates
Winovus manufactures nano-scale structured substrates in Singapore, and we support global companies in their Deep Tech applications. We design and fabricate micro-and nano-scale patterns that add optical, functional, and mechanical properties to your optical devices and components.
Customized polymer fluidic applications
z-microsystems is specialized in providing microstructures on polymer chips for fluidic application. z-microsystems has its tool shop to produce precision injection molds to deliver high quality chips. With its in-house technologies and know-how, z-microsystems supports customers around the world from development phase through prototypes to mass production. Post molding processes like bonding and coating could be included in a full service collaboration with this microfluidic company.
Fabricating high-quality microfluidic chips is essential for ensuring the performance and reliability of microfluidic systems, especially when accuracy in channel dimensions is crucial for fluid behavior. Choosing the right materials, whether glass, polymer, or PDMS, influences the device’s stability and precision. Collaborating with a trusted manufacturer is key to successfully developing and scaling your custom designs. Elveflow, with its extensive expertise and innovative solutions, is an ideal partner to support your microfluidic device fabrication needs. Feel free to connect with Elveflow to elevate your project.
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