SET-UP TIME : 15-20 MIN / DIFFICULTY : *****
This application note shows how to perform a fast microfluidic medium switch (drugs, samples, etc) in an hypothetical chemical or biological environment, performed with an Elveflow® pressure & flow control instrument (OB1) as shown in these pictures:
* We propose another configuration (using an Elveflow OB1 and am Elveflow MUX standard) to perform a microfluidic fast medium switch. Click here to see the Application Note.
We also recommend to see the following review comparing the two configurations (OB1 or OB1+MUX).
For fast microfluidic medium switch in perfusion chambers or one inlet microfluidic chips, discover our dedicated Perfusion Pack.
This picture shows the microfluidic setup that will be used in this application note.
The following diagram illustrates the complete chain of elements involved in this application note. You will need to assemble all these parts to set up your experiment:
Using the Elveflow® smart interface to perform a fast microfluidic medium switch:
Make sure that all the cables and tubing are well connected to your Elveflow device (USB cable, 24V DC, etc).
Perform leakage tests and remove any air bubbles before starting your experiment to ensure a good flow regulation. Knowing what fitting is best suited for your needs is a first step towards success. If you’re not familiar with microfluidic fittings, you may read our specific tutorials.
In order to monitor the pressure to perform a fast medium switch, it is necessary to follow the next steps:
Set the desired maximum and minimum shown parameters on the display window for pressure and flow rate and press the play icon to launch the pressure and flow rate profiles display.
Select the channels you want to display by ticking the corresponding boxes on the channel display selection block.
Congratulations! You’ve achieved an ultrafast medium switch using an Elveflow® OB1!
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Do you want tips on how to best set up your microfluidic experiment? Do you need inspiration or a different angle to take on your specific problem? Well, we probably have an application note just for you, feel free to check them out!
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