This month in the science of manipulating tiny amounts of fluids in minuscule channels, we explore recent developments that highlight the transformative power of this field, impacting everything from medical breakthroughs to innovative business cards. Let’s delve into the latest advancements and their scientific significance.
Due to PDMS deformation under high pressures, alternative techniques must be considered for high-pressure microfluidics experiments. In this paper, the authors introduce new approaches for experiments that require precise control over fluid dynamics under extreme conditions. This capability is essential for applications such as chemical synthesis, high-throughput screening, and studying the behavior of fluids and particles at high pressures. This research paper, conducted by Carlie Rein et al. from the Center for Engineering in Medicine and Surgery, presents a comprehensive protocol that ensures these conditions without compromising performance or reliability. From PDMS Mold preparation to Epoxy Molding and Release, the article details each step of the microfabrication process. By enabling precise control and manipulation of fluids under extreme conditions (here up to 500 psi), these devices can significantly enhance the capabilities of scientific experiments and industrial processes.
Discover more about this fascinating research in the full publication!
A recent study published in Advanced Science by Saumey Jain et al., details a novel microfluidic device that enhances the conversion of connective tissue cells into neural stem cells, significantly advancing the potential for personalized cell-based therapies for neurodegenerative diseases. Developed by researchers at KTH Royal Institute of Technology, the device utilizes polydimethylsiloxane (PDMS) to create a confined environment that accelerates the transformation process from Fibroblasts into induced pluripotent stem cells (iPSCs), and their subsequent differentiation into neural stem cells (NSCs) offering a more efficient and cost-effective method compared to traditional techniques. This innovation could lower the costs and improve the accessibility of treatments for conditions like Alzheimer’s and Parkinson’s, representing a significant step forward in medical research.
For more information, read the full article.
Microfluidics isn’t confined to the laboratory; it has also made its way into everyday life in surprising ways. Saren Tasciyan’s innovative business card is a perfect example. This card uses microfluidic channels to reveal hidden information when exposed to water, demonstrating the versatility and creativity of microfluidic applications.
The card contains a network of microscopic pathways that guide the flow of water, activating a series of chemical reactions or revealing hidden text and images. This interactive design showcases the potential of microfluidics in creating engaging and functional everyday items. It’s a brilliant fusion of science and art, illustrating how microfluidics can transform even the simplest objects into something extraordinary.
Get more info on his project page!
Stay tuned for more Hot News in the fascinating world of Microfluidics, where tiny channels lead to significant breakthroughs and endless possibilities!
For any help to determine what microfluidic instruments you need, you can contact us! Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.
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