Cultivate and study cells in a controlled microenvironment with a chemical gradient generated within a microfluidic chip, closely mimicking in vivo conditions for accurate chemotaxis experiments.
Conduct chemotaxis studies with precise gradient control, reduced reagent use, and reliable quantification, making your experiments cost-effective and productive.
Ensure stable chemical gradients over time with laminar flow in microchannels, providing consistent results for long-term experiments.
Customize your experiments with the microfluidic chip that fits your needs, optimizing material, gradient formation, and cell seeding for accurate outcomes.
Streamlined Setup for Advanced Research
The Microfluidic Chemotaxis Assay Use Case includes all the essential components you need to quickly and efficiently set up your experiments. From the OB1 flow controller to gradient-generating chips, this comprehensive use case is designed to simplify the process of studying chemotaxis in various cell types, such as HUVECs or neutrophils.
Using microfluidics in chemotaxis assays offers several advantages over traditional methods. For example, microfluidic systems require significantly less reagent, reducing costs while maintaining high precision. Additionally, the ability to create stable, long-term chemical gradients makes these systems ideal for mimicking in vivo conditions, which can lead to more accurate and translatable results.
Integrated and Customizable System
This use case is designed for compatibility and ease of use. The all-in-one system ensures that all components work seamlessly together, controlled by a single software platform. Whether you are an experienced researcher or new to microfluidics, our experts are available to guide you through the setup process, ensuring your experiments are up and running without delay.
For more complex experimental needs, additional microfluidic chips can be integrated into your setup. This flexibility allows for the creation of more sophisticated platforms, enabling you to conduct a broader range of studies.
The typical Microfluidic Chemotaxis Assay Use Case includes the following components:
This setup offers a robust and reliable foundation for your chemotaxis studies, ensuring precise control and high-quality results.
Microfluidic chemotaxis assays are particularly useful for studying cell migration in response to chemical gradients. The ability to precisely control these gradients within a microfluidic chip allows for detailed analysis of chemotaxis in various cells, including immune cells like neutrophils and endothelial cells such as HUVECs.
The platform’s flexibility also allows for customization to meet specific research needs. For example, the gradient chip can be made from materials such as Cyclic Olefin Copolymer (Topas COC) or polystyrene (PS), with the option to hydrophilize the material to improve cell seeding. Additional pumping channels and flow rate sensors can also be added to enhance the system’s capabilities.
Microfluidic technology has revolutionized chemotaxis studies by offering greater precision, reduced reagent usage, and better mimicry of in vivo conditions compared to traditional methods. The laminar flow within microchannels ensures that chemical gradients remain stable over time, which is essential for accurate chemotaxis analysis.
Moreover, microfluidic systems allow for high-throughput studies, making it possible to conduct multiple experiments simultaneously while maintaining control over experimental conditions. This efficiency is particularly valuable in drug discovery and other applications where time and resources are critical.
Our Microfluidic Chemotaxis Assay Use Case is fully customizable to meet the specific needs of your research. Whether you require additional sensors, different chip materials, or specific configurations, our experts are available to help you tailor the system to your exact specifications.
For more information or to discuss your requirements, please contact our experts.
– Explore our other use cases for a variety of applications –
For any help to determine what microfluidic instruments you need, you can contact us! Our experts will help you build the best microfluidic setup for your application, with our state-of-the-art microfluidic line.
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