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Blog type: Microfluidic Updates

High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq

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High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq The article “High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq” published in Nature Biotechnology details a significant advancement in spatial transcriptomics, a technique crucial for understanding cell differentiation and tissue development. The study introduces an innovative technique called spatial … Continued

Microfluidic potential for Food Industry

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Microfluidic potential for Food Industry The food industry is experiencing a technological transformation driven by the demand for more precise, efficient, and scalable methods to ensure product quality, safety, and sustainability. Microfluidics, a promising technology, has gained attention due to its ability to manipulate fluids at the microscale, making it highly applicable to food-related processes. … Continued

Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability

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Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability The article titled “Evolution of the structure of lipid nanoparticles for nucleic acid delivery: From in situ studies of formulation to colloidal stability” published in the Journal of Colloid and Interface Science, explores the structural … Continued

Spatial epigenome–transcriptome co-profiling of mammalian tissues

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Spatial epigenome–transcriptome co-profiling of mammalian tissues The article titled “Spatial Epigenome–Transcriptome Co-Profiling of Mammalian Tissues” published in Nature, presents groundbreaking methodologies that integrate spatial epigenomics and transcriptomics to co-profile chromatin accessibility and gene expression in the same tissue sections. This dual-layered approach provides a more detailed understanding of gene regulation within the tissue architecture, enabling … Continued

Interindividual- and blood-correlated sweat phenylalanine multimodal analytical biochips for tracking exercise metabolism

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Interindividual- and blood-correlated sweat phenylalanine multimodal analytical biochips for tracking exercise metabolism The article titled “Interindividual- and blood-correlated sweat phenylalanine multimodal analytical biochips for tracking exercise metabolism“, published in Nature Communications, presents a novel wearable multimodal biochip designed to monitor phenylalanine (Phe) and other sweat indicators during exercise, offering valuable insights into metabolism and health. … Continued

Large-scale perfused tissues via synthetic 3D soft microfluidics

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Large-scale perfused tissues via synthetic 3D soft microfluidics The article titled “Large-scale perfused tissues via synthetic 3D soft microfluidics,” published in Nature Communications, presents an innovative approach to creating vascularized tissue constructs using synthetic microfluidics. This research addresses a significant challenge in regenerative medicine: the need for a robust vascular network to support large tissue … Continued

Shaping a Soft Future: Patterning Liquid Metals

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Shaping a Soft Future: Patterning Liquid Metals Introduction The review presents a detailed exploration of techniques for controlling and patterning liquid metals, particularly gallium-based alloys. Liquid metals (LMs) combine the fluidity of liquids with the conductivity of metals, making them ideal for applications in stretchable electronics, soft robotics, and other emerging fields. The unique properties … Continued

A Critical Review on Latest Innovations and Future Challenges of Electrochemical Technology for the Abatement of Organics in Water

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A Critical Review on Latest Innovations and Future Challenges of Electrochemical Technology for the Abatement of Organics in Water Introduction Electrochemical technology has emerged as a powerful tool for treating organic pollutants in water. This review explores the latest innovations in this field and addresses the future challenges that need to be overcome to enhance … Continued

Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens

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Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens The article published in Nature Nanotechnology outlines a breakthrough in the development of a novel molecular diagnostic platform, “QolorEX,” which integrates nanoplasmonic amplification with microfluidics to enable rapid colorimetric quantification of nucleic acid biomarkers from pathogens. This innovation addresses the limitations … Continued

A Field Guide to Flow Chemistry for Synthetic Organic Chemists

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A Field Guide to Flow Chemistry for Synthetic Organic Chemists Introduction Flow chemistry has emerged as a transformative approach for synthetic organic chemistry, offering significant advantages over traditional batch processes. These benefits include improved mass and heat transfer, enhanced safety, increased efficiency, reduced waste, and superior scalability and reproducibility. Historically, flow chemistry was perceived as … Continued

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